Studying the role of Arg (B22) His and Arg (B22) His /Lys (B29) His mutations on the structural and functional Properties of human insulin with the aim of introducing new pharmaceutical analogs.

Document Type : Animal Research

Researchers

• Zahra Bahrami ¹
• Reza Yousefi ²
• saeid bouzari ³
• Ali Akbar Moosavi-Movahedi ²

¹ Department of Biochemistry, Institute Biochemistry and Biophysics, University of Tehran, Tehran, Iran

² Institute of Biochemistry and Biophysics (IBB), University of Tehran, Tehran, Iran

³ Pasteur Institute of Iran, Tehran, Iran

Ministerial Ethics Committee

Approval ID

• Recombinant insulin
• Proinsulin
• Biological activity
• Site directed mutagenesis
• Diabetes

Main Subjects

• Other